The lower extremities, particularly the feet, are the most frequently affected body part in term of diabetic complications. Diabetics often show local lack of sensitivity, due to peripheral neuropathy, microcirculatory impairment and extreme proneness to infection. These conditions frequently lead to foot skin lesions, which should be handled in time and with great care, since if left untreated tey may deteriorate to a various serious extent, leading ultimately to devastating surgical intervention. It is essential to control localized epidermal tropism in diabetic foot by improving the physiological keratinization process, preserving and restoring a functional hydro-lipidic barrier as well as supporting an optimal post-ulcerous re-epithelialization.
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