Research to prevent and slow down neurodegenerative diseases
Modern neuroscience focuses on the fundamental role of non-neuronal cells, such as microglia, astrocytes and mastocytes, for central nervous system balance. Although not the primary cause of neurodegenerative diseases, these cells contribute considerably to the neuroinflammation and oxidative stress processes. They also accelerate neuronal damage and, as a result, the evolution of these illnesses.
A neuroinflammatory cross-talk is progressively activated between microglia, astrocytes, and mast cells, with potential neurodegenerative damage.
Our research focuses on innovative strategies for modulating this cell activity and controlling oxidative stress, to preserve neuronal functions. This approach offers new opportunities for preventing and slowing the advancement of neurodegenerative processes and immunosenescence, thereby improving the quality of life of patients affected by neurodegenerative diseases.