Research to maintain neuro-metabolic balance
Several metabolic disorders, including type 2 diabetes and metabolic syndrome, are associated with chronic low-grade inflammation. This entails immune, vascular and nervous system dysfunction. Chronic inflammation plays a key role in the development of peripheral neuropathy, a progressive complication that affects the peripheral nervous and muscular systems.
Meta-inflammation, a chronic form of metabolism-related inflammation, is at the heart of the link between obesity and pain. The accumulation of fat triggers this persistent inflammatory state: damaged adipocytes release pro-inflammatory factors that through the systemic circulation, sensitize peripheral pain neurons, contributing to a viciousinflammation and hypersensitivity.
Metabolic support, early identification, and control ‘as nature intended’ are crucial for preventing the progression of peripheral neuropathy and help improve the quality of life of patients with metabolic disorders.